Achieving and Maintaining Flow State with Plant Medicine

What is Flow State?

Flow state, also known as “being in the zone,” is a mental state in which a person is fully absorbed in an activity, resulting in a heightened sense of focus, enjoyment, and intrinsic motivation (Csikszentmihalyi, 1990). This state is often associated with peak performance in various domains, such as sports, arts, and professional settings.

The concept of flow state was first introduced by Hungarian psychologist Mihaly Csikszentmihalyi in the 1970s. According to Csikszentmihalyi (1990), flow state has several key characteristics, including:

  • Intense and focused concentration on the present moment
  • Merging of action and awareness
  • Loss of self-consciousness and a sense of unity with the activity
  • A sense of personal control over the situation or activity
  • Distortion of the experience of time (e.g., time seeming to slow down or speed up)
  • Immediate feedback on one’s performance
  • The activity being intrinsically rewarding
  • A balance between the perceived challenges of the task and one’s perceived skills
  • A feeling of effortless performance

The Purpose of Flow State

Flow state is believed to serve several important functions. First, it has been linked to increased well-being and life satisfaction (Nakamura & Csikszentmihalyi, 2009). When individuals are in flow, they tend to experience a heightened sense of enjoyment, fulfillment, and overall happiness.

Second, flow state is associated with enhanced performance and creativity (Csikszentmihalyi, 1997; Kotler & Wheal, 2017). In this state, individuals are able to access a higher level of cognitive functioning, leading to improved problem-solving, decision-making, and creative insights.

Finally, flow state may also promote personal growth and self-discovery (Csikszentmihalyi, 2000). By allowing individuals to lose themselves in an activity and experience a sense of unity with their surroundings, flow can facilitate a deeper understanding of one’s true passions and strengths.

The concept of flow state has captivated the minds of not only high-performers but also those who seek to explore the depths of human potential and consciousness. Flow state is a powerful psychological phenomenon that transcends the boundaries of ordinary consciousness, providing a glimpse into the extraordinary capabilities of the human mind. As our understanding of flow state deepens, the exploration of plant medicine and its potential to facilitate this state becomes an increasingly compelling area of inquiry.

Plant medicine, which encompasses a diverse array of herbs, fungi, and other natural substances, has been revered by indigenous cultures for centuries. These ancient traditions recognized the potential of plant medicine to enhance awareness, foster spiritual growth, and bring about profound healing. In our modern world, the wisdom of these ancient practices is being rediscovered, leading to a resurgence of interest in the power of plants to support mental health and well-being.

One of the most intriguing aspects of plant medicine is the potential for these natural substances to interact with human consciousness in a way that facilitates the experience of flow state. As we delve into the world of plant medicine, we are met with a sense of curiosity and awe, pondering the possibility that the consciousness of these plants may intertwine with our own, guiding us towards a state of heightened awareness, creativity, and connection.

The fusion of plant consciousness with human consciousness, though a concept shrouded in mystery, offers a tantalizing perspective on the relationship between nature and the human mind. As we open ourselves to the potential of plant medicine, we embark on a journey of discovery, unearthing the secrets of these ancient allies and their role in facilitating the experience of flow state.

Research on plant medicine and its potential role in achieving and maintaining flow state is still in its infancy. However, the anecdotal evidence and preliminary studies provide a compelling foundation for further exploration. The use of plants such as Lion’s Mane mushrooms, Rhodiola rosea, and various Chinese herbs has been linked to enhanced cognitive function, reduced stress, and improved focus, all of which can contribute to the experience of flow state.

Moreover, the practice of using plant medicine to achieve flow state is not limited to the consumption of these substances. The very act of engaging with plants, whether through cultivation, preparation, or ritual, can itself serve as a gateway to flow. The mindful interaction with plants fosters a sense of presence, intention, and reverence, qualities that align with the essence of flow state.

When considering plant medicine to facilitate flow state, consider the following guidelines:

Begin by setting an intention

As you embark on your journey with plant medicine, establish a clear intention for your experience. This may involve identifying the specific aspects of flow state you wish to cultivate, such as creativity, focus, or mental clarity.

Create a supportive environment

Ensure that your surroundings are conducive to achieving flow state, with minimal distractions and an atmosphere that fosters relaxation and focus.

Develop a ritual or practice

Engage with plant medicine in a mindful and intentional manner, whether through the preparation of tea, the use of aromatherapy, or the cultivation of a personal relationship with the plants themselves.

Monitor your progress

Keep a journal to document your experiences with plant medicine and its impact on your ability to achieve and maintain flow state. This will help you to fine-tune your approach and deepen your understanding of the plants and their effects on your consciousness.

Embrace curiosity and remain open to learning

As you explore the world of plant medicine, approach your experiences with curiosity and a willingness to learn. Recognize that your relationship with these plants may evolve over time, and be open to the insights and wisdom they have to offer.

Combine plant medicine with complementary practices

Consider incorporating other practices that support flow state, such as meditation, mindfulness, breathwork, or physical exercise. These activities can help to enhance the benefits of plant medicine and create a synergistic effect in cultivating flow.

Respect the plants and their wisdom

As you work with plant medicine, remember to honor the wisdom and healing power of these natural substances. Approach your interactions with respect and gratitude, recognizing the sacred relationship between humans and the natural world.

Stay informed and educated

As research on plant medicine and its role in achieving and maintaining flow state continues to emerge, stay up-to-date on the latest findings and developments. This will enable you to make informed decisions about your use of plant medicine and ensure that your practices remain safe and effective.

Share your experiences and insights

As you delve into the world of plant medicine and flow state, consider sharing your experiences and insights with others. This can help to foster a sense of community and support, as well as contribute to the collective understanding of the potential of these powerful natural substances.

The exploration of plant medicine as a means of achieving and maintaining flow state offers a captivating and thought-provoking journey into the realms of human potential and consciousness. As we open ourselves to the wisdom of these ancient allies, we are guided towards a state of heightened awareness, creativity, and connection, where the boundaries of ordinary consciousness dissolve, and we are left with a sense of being in harmony with the world around us.

The fusion of plant consciousness with our own consciousness invites us to ponder the intricate and interconnected web of life, and the role that these natural substances play in shaping our experiences and perceptions. As we delve deeper into the mysteries of plant medicine and flow state, we are reminded of the profound power of nature to heal, inspire, and transform our lives

Choosing Plants to Facilitate Flow States

Various plant medicines have been traditionally used to promote altered states of consciousness, which may share similarities with the flow state. In recent years, research has begun to explore the potential of these natural substances to enhance psychological well-being, cognition, and performance. Some of the most promising plant medicines for achieving and maintaining flow state include:

Psilocybin-containing mushrooms (Psilocybe spp.)

Psilocybin, the active compound in “magic mushrooms,” has gained significant attention in recent years for its potential therapeutic benefits in treating mental health conditions such as depression, anxiety, and PTSD (Carhart-Harris et al ., 2016; Johnson et al., 2014). In addition to these therapeutic applications, psilocybin has been shown to induce a state of heightened awareness, increased creativity, and cognitive flexibility (Studerus et al., 2012), which may share similarities with the flow state.

A study by MacLean et al. (2011) found that psilocybin-induced mystical experiences were associated with long-lasting increases in openness, a personality trait linked to creativity and cognitive flexibility. Additionally, a study by Preller et al. (2019) demonstrated that psilocybin administration led to increased neural connectivity, which may underlie the enhanced creative thinking and problem-solving abilities reported by users.

While more research is needed to establish a direct link between psilocybin and flow state, these findings suggest that psilocybin-containing mushrooms may have the potential to facilitate flow-like experiences and enhance performance in various domains.

Ayahuasca (Banisteriopsis caapi and Psychotria viridis)

Ayahuasca is a powerful plant medicine traditionally used by indigenous Amazonian cultures for its healing and visionary properties. The brew contains a combination of two plants: Banisteriopsis caapi, which contains monoamine oxidase inhibitors (MAOIs), and Psychotria viridis, which contains the potent hallucinogen N,N-dimethyltryptamine (DMT).

Ayahuasca has been shown to induce profound alterations in consciousness, including heightened sensory perception, emotional release, and mystical experiences (de Araujo et al., 2012). While the relationship between ayahuasca and flow state has not been explicitly studied, the brew’s ability to promote deep introspection, emotional healing, and enhanced creativity (Frecska et al., 2016) suggests that it may hold potential for facilitating flow-like states.

Cannabis (Cannabis sativa)

Cannabis has long been used for its psychoactive and medicinal properties, and recent research has begun to elucidate the potential benefits of various cannabinoids, such as THC and CBD, for mental health and cognitive function (Blessing et al., 2015; Russo, 2011). While the relationship between cannabis and flow state has not been extensively studied, anecdotal reports suggest that some users experience increased focus, creativity, and enjoyment of activities while under the influence of the plant.

A study by Morgan et al. (2010) found that cannabis users with higher levels of the cannabinoid CBD in their system exhibited better cognitive performance and less impairment of short-term memory compared to users with higher levels of THC. This finding suggests that specific cannabinoids or strains of cannabis may be more conducive to flow-like states than others.

Rhodiola rosea

Rhodiola rosea is a natural adaptogen that has been used for centuries to increase physical and mental endurance, reduce stress, and improve cognitive function (Panossian et al., 2010). Research has shown that Rhodiola can enhance cognitive performance under stress, improve mood, and reduce mental fatigue (Darbinyan et al., 2000; Spasov et al., 2000).

While the connection between Rhodiola and flow state has not been explicitly studied, the herb’s ability to promote mental clarity, focus, and resilience under stress suggests that it may be a valuable tool for achieving and maintaining flow.

L-theanine

L-theanine is an amino acid found in green tea that has been shown to promote relaxation, reduce stress, and improve cognitive function (Nobre et al., 2008; White et al., 2016). Research has demonstrated that L-theanine can enhance alpha brainwave activity, which is associated with a state of relaxed alertness (Nobre et al ., 2008). This relaxed, yet focused mental state is similar to the flow state, suggesting that L-theanine may be a useful supplement for facilitating flow experiences.

One study by Haskell et al. (2008) found that L-theanine administration led to improvements in both attention and reaction time, indicating that it may support cognitive performance and focus. Additionally, L-theanine has been shown to have synergistic effects when combined with caffeine, resulting in enhanced cognitive performance and reduced susceptibility to distractions (Haskell et al., 2008; Owen et al., 2008).

Lion’s Mane (Hericium erinaceus)

Lion’s mane is an edible mushroom with a long history of use in traditional Chinese medicine. In recent years, it has gained attention for its potential cognitive-enhancing effects. Research suggests that lion’s mane contains compounds called hericenones and erinacines, which can stimulate the production of nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) (Lai et al., 2013; Mori et al., 2008). These growth factors play a crucial role in promoting the growth, survival, and maintenance of neurons, which are essential for cognitive function and mental well-being.

In the context of flow state, lion’s mane may help to enhance focus, mental clarity, and overall cognitive performance. A study by Mori et al. (2009) found that lion’s mane supplementation improved cognitive function in older adults with mild cognitive impairment. Although more research is needed to understand the full extent of lion’s mane’s cognitive-enhancing effects, its potential to promote neuronal health and function suggests that it may be a useful tool for facilitating flow experiences.

Caffeine

Caffeine is a natural stimulant found in coffee, tea, and various other plant-based sources. It is one of the most widely consumed psychoactive substances globally and is well-known for its ability to increase alertness and decrease fatigue. Caffeine’s primary mechanism of action involves blocking the action of adenosine, a neurotransmitter that promotes relaxation and sleepiness (Fredholm et al., 1999).

In the context of flow state, caffeine may help to enhance focus, attention, and cognitive performance, making it easier to become fully immersed in an activity. Research has shown that caffeine can improve attention, reaction time, and various aspects of cognitive function (Nehlig, 2010). Moreover, caffeine has been shown to have synergistic effects when combined with L-theanine, an amino acid found in green tea, resulting in enhanced cognitive performance and reduced susceptibility to distractions (Haskell et al., 2008; Owen et al., 2008).

By promoting alertness and focus, caffeine may help individuals overcome the initial barriers to entering a flow state, such as mental fatigue or lack of concentration. However, it is essential to consume caffeine in moderation, as excessive intake can lead to negative side effects such as increased anxiety, jitteriness, and sleep disturbances, which may counteract its potential benefits for flow.

Ginkgo Biloba

Ginkgo biloba, an ancient tree species native to China, has been used in traditional Chinese medicine for centuries to enhance memory and cognitive function. The leaves of the ginkgo tree contain various bioactive compounds, such as flavonoids and terpenoids, which have been shown to possess antioxidant and anti-inflammatory properties (Mahadevan & Park, 2008).

In the context of flow state, ginkgo biloba may help improve cognitive performance, attention, and overall mental function. Numerous studies have demonstrated the cognitive-enhancing effects of ginkgo biloba, particularly in older adults with age-related cognitive decline (Yancheva et al., 2009; Mix & Crews Jr, 2002). Research suggests that ginkgo biloba may work by increasing blood flow to the brain, protecting neurons from oxidative stress, and modulating neurotransmitter systems (Ahlemeyer & Krieglstein, 2003).

Ginseng (Panax spp.)

Ginseng, particularly the Panax species such as Panax ginseng (Asian ginseng) and Panax quinquefolius (American ginseng), has been used in traditional Chinese medicine as an adaptogen and general tonic for enhancing vitality, stamina, and cognitive function. Ginseng contains various bioactive compounds known as ginsenosides, which have been shown to possess antioxidant, anti-inflammatory, and neuroprotective properties (Kim, 2012).

In the context of flow state, ginseng may help improve cognitive performance, mood, and stress resilience. Research has shown that ginseng can enhance various aspects of cognitive function, such as memory, attention, and executive function (Scholey et al., 2010; Reay et al., 2006). Moreover, ginseng has been found to reduce stress and anxiety, making it easier for individuals to enter and maintain a state of flow (Lee et al., 2011).

Rhodiola (Rhodiola rosea)

Rhodiola rosea, also known as golden root or Arctic root, is a perennial plant native to the high-altitude regions of Asia and Europe. In traditional Chinese medicine, rhodiola has been used as an adaptogen to enhance physical and mental performance, as well as to combat fatigue and stress.

In the context of flow state, rhodiola may help improve cognitive function, mood, and stress resilience. Research has shown that rhodiola can enhance cognitive performance, particularly during periods of stress and fatigue (Darbinyan et al., 2000; Spasov et al., 2000). Moreover, rhodiola has been found to have antidepressant and anxiolytic effects, which may further facilitate the entry into a flow state (Mao et al., 2015; Amsterdam et al., 2012).

Practical Considerations

Establish a consistent routine

To maximize the benefits of plant medicine in achieving flow state, it’s important to establish a consistent routine. Many plant medicines work best when taken regularly over an extended period. Consistency allows the body to adapt to the compounds, leading to more significant cognitive and mood-enhancing effects. Develop a schedule for taking your chosen plant medicine and stick to it to reap the full benefits.

Combine plant medicine with mindfulness practices

Mindfulness practices, such as meditation, yoga, or deep breathing exercises, can help individuals enter a flow state by training the mind to focus and be present in the moment. Combining plant medicine with mindfulness practices can enhance the effects of both, making it easier to achieve and maintain flow state. For example, you can take your chosen plant medicine 30-60 minutes before engaging in a mindfulness practice to create a synergistic effect.

Optimize your environment

Creating an environment that is conducive to flow state is crucial. This includes minimizing distractions, ensuring a comfortable and ergonomic workspace, and setting the right ambiance with soft lighting, calming scents, or background music. By taking plant medicine in an environment that supports focus and productivity, you will further enhance its potential to help you achieve flow state.

Set clear goals and intentions

Having clear goals and intentions for your work or activity can help you enter and maintain a flow state by providing a sense of direction and purpose. When you know what you want to accomplish and why, it becomes easier to stay focused and engaged. Before starting your work or activity, take a moment to set your intentions and visualize the desired outcome. This can help prime your mind for optimal performance and flow.

Monitor your progress and adjust as needed

As you incorporate plant medicine into your routine to achieve flow state, it’s essential to monitor your progress and adjust your approach as needed. Track any noticeable changes in your cognitive function, mood, or ability to achieve flow state. If you’re not experiencing the desired effects or encounter any adverse side effects, consult with your healthcare professional to adjust the dosage, switch to a different plant medicine, or explore other strategies for achieving flow state.

Combine plant medicine with brain-boosting nutrition

A well-balanced and nutrient-dense diet can have a significant impact on cognitive function and mood. Combining plant medicine with a diet rich in brain-boosting nutrients, such as omega-3 fatty acids, antioxidants, and B vitamins, can further enhance your ability to achieve flow state. Foods like fatty fish, nuts, seeds, leafy greens, and whole grains can provide essential nutrients that support optimal brain function and synergize with the effects of plant medicine.

Incorporate physical activity

Physical activity has been shown to improve cognitive function, mood, and overall well-being. Engaging in regular physical activity can help create an ideal mental state for achieving flow. Exercise can increase the production of brain-derived neurotrophic factor (BDNF), a protein that supports the growth and maintenance of neurons, which is essential for learning and memory. By combining plant medicine with regular physical activity, you can optimize the conditions necessary for achieving and maintaining flow state.

Practice patience and self-compassion

Achieving flow state may not happen immediately, and it’s essential to practice patience and self-compassion during the process. Plant medicine can help create the right conditions for flow, but it may take time to notice significant changes in your cognitive function, mood, and ability to enter flow state. Be kind to yourself and remember that the journey to achieving flow state is a gradual process that requires consistent effort and self-care.

Specific Preparations

Herbal teas and infusions

Preparing a tea or infusion from dried or fresh plant material is a popular and straightforward method to consume plant medicine. Simply steep the plant material in hot water for a few minutes, then strain and drink the liquid. The soothing ritual of preparing and sipping herbal tea can also contribute to a sense of relaxation and mindfulness.

Tinctures and extracts

Tinctures and extracts are concentrated forms of plant medicine made by soaking plant material in alcohol or glycerin to extract the active compounds. These liquid preparations can be taken sublingually (under the tongue), added to water, or mixed into food or beverages. Tinctures and extracts provide a more potent and fast-acting form of plant medicine compared to teas and infusions.

Capsules and tablets

Many plant-based supplements are available in capsule or tablet form, offering a convenient and standardized method of consumption. This allows for easy and consistent dosing, which can be especially beneficial when using plants to achieve flow state.

Aromatherapy

Essential oils extracted from plants can be used in aromatherapy to support flow state. Diffusing essential oils or applying them topically (diluted with a carrier oil) can provide a range of benefits, including relaxation, mental clarity, and mood enhancement. Some plants, such as lavender, rosemary, and lemon balm, are known for their calming and cognition-boosting properties when used in aromatherapy.

Topical applications

Some plant medicine can be applied topically in the form of creams, salves, or lotions. For instance, CBD-infused products have been shown to promote relaxation and help alleviate stress and anxiety, which can support the achievement of flow state.

Edibles

Edible forms of plant medicine, such as chocolates, gummies, or baked goods, can be an enjoyable and discreet way to consume plant medicine. These products often contain a standardized dose of active compounds and can offer a more controlled and consistent method of consumption.

Inhalation

Some plants, like cannabis, can be consumed through inhalation, either by smoking or vaporizing. This method allows the active compounds to enter the bloodstream rapidly, providing a fast-acting and potent effect that can support flow state.

Synergy blends

Combining different plants or plant extracts can create a synergistic effect, enhancing their individual benefits and supporting flow state. For example, combining Lion’s Mane mushroom with caffeine or other adaptogenic herbs can create a more potent cognitive-enhancing effect.

When using plant medicine to achieve flow state, it’s essential to consider the specific plant and its traditional use, as well as the most suitable method of consumption. Always consult with a qualified healthcare professional before incorporating any plant medicine into your routine, and remember that individual responses may vary.

References:

Csikszentmihalyi, M. (1990). Flow: The Psychology of Optimal Experience. New York: Harper & Row. [https://www.amazon.com/Flow-Psychology-Experience-Perennial-Classics/dp/0061339202]

Nakamura, J., & Csikszentmihalyi, M. (2009). Flow Theory and Research. In S. J. Lopez & C. R. Snyder (Eds.), Oxford Handbook of Positive Psychology (pp. 195-206). Oxford University Press. [https://www.oxfordhandbooks.com/view/10.1093/oxfordhb/9780195187243.001.0001/oxfordhb-9780195187243-e-17]

Csikszentmihalyi, M. (1997). Creativity: Flow and the Psychology of Discovery and Invention. New York: HarperCollins. [https://www.amazon.com/Creativity-Flow-Psychology-Discovery-Invention/dp/0062283251]

Kotler, S., & Wheal, J. (2017). Stealing Fire: How Silicon Valley, the Navy SEALs, and Maverick Scientists Are Revolutionizing the Way We Live and Work. HarperCollins. [https://www.amazon.com/Stealing-Fire-Maverick-Scientists-Revolutionizing/dp/0062429655]

Csikszentmihalyi, M. (2000). Beyond Boredom and Anxiety: Experiencing Flow in Work and Play. San Francisco: Jossey-Bass. [https://www.amazon.com/Beyond-Boredom-Anxiety-Experiencing-25th-Anniversary/dp/0787951404]

Carhart-Harris, R. L., et al. (2016). Psilocybin with psychological support for treatment-resistant depression: an open-label feasibility study. The Lancet Psychiatry, 3(7), 619-627. [https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(16)30065-7/fulltext]

Johnson, M. W., et al. (2014). Pilot study of the 5-HT2AR agonist psilocybin in the treatment of tobacco addiction. Journal of Psychopharmacology, 28(11), 983-992. [https://journals.sagepub.com/doi/full/10.1177/0269881114548296]

Studerus, E., et al. (2012). Acute, subacute and long-term subjective effects of psilocybin in healthy humans: a pooled analysis of experimental studies. Journal of Psychopharmacology, 26(11), 1434-1452. [https://journals.sagepub.com/doi/full/10.1177/0269881112444246]

MacLean, K. A., et al. (2011). Mystical experiences occasioned by the hallucinogen psilocybin lead to increases in the personality domain of openness. Journal of Psychopharmacology, 25(11), 1453-1461. [https://journals.sagepub.com/doi/10.1177/0269881111420188]

Preller, K. H., et al. (2019). Effective connectivity changes in LSD-induced altered states of consciousness in humans. Proceedings of the National Academy of Sciences, 116(7), 2743-2748. [https://www.pnas.org/content/116/7/2743]

de Araujo, D. B., et al. (2012). Seeing with the eyes shut: Neural basis of enhanced imagery following Ayahuasca ingestion. Human Brain Mapping, 33(11), 2550-2560. [https://onlinelibrary.wiley.com/doi/full/10.1002/hbm.21381]

Frecska, E., et al. (2016). Enhancement of creative expression and entoptic phenomena as after-effects of repeated ayahuasca ceremonies. Journal of Psychoactive Drugs, 48(4), 233-242. [https://www.tandfonline.com/doi/full/10.1080/02791072.2016.1194557]

Blessing, E. M., et al. (2015). Cannabidiol as a potential treatment for anxiety disorders. Neurotherapeutics, 12(4), 825-836. [https://link.springer.com/article/10.1007%2Fs13311-015-0387-1]

Russo, E. B. (2011). Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects. British Journal of Pharmacology, 163(7), 1344-1364. [https://bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/j.1476-5381.2011.01238.x]

Morgan, C. J., et al. (2010). Impact of cannabidiol on the acute memory and psychotomimetic effects of smoked cannabis: naturalistic study. The British Journal of Psychiatry, 197(4), 285-290. [https://www.cambridge.org/core/journals/the-british-journal-of-psychiatry/article/abs/impact-of-cannabidiol-on-the-acute-memory-and-psychotomimetic-effects-of-smoked-cannabis-naturalistic-study/3C7E9D1C9E5DF5D1F5C09F61E846255C]

Panossian, A., et al. (2010). Rosenroot (Rhodiola rosea): traditional use, chemical composition, pharmacology and clinical efficacy. Phytomedicine, 17(7), 481-493. [https://www.sciencedirect.com/science/article/abs/pii/S0944711310000257]

Darbinyan, V., et al. (2000). Rhodiola rosea in stress-induced fatigue—a double-blind, cross-over study. Phytomedicine, 7(5), 365-371. [https://www.sciencedirect.com/science/article/abs/pii/S0944711300800556]

Spasov, A. A., et al. (2000). A double-blind, placebo-controlled pilot study of the stimulating and adaptogenic effect of Rhodiola rosea SHR-5 extract on the fatigue of students caused by stress during an examination period with a repeated low-dose regimen. Phytomedicine, 7(2), 85-89. [https://www.sciencedirect.com/science/article/abs/pii/S0944711300800428]

Nobre, A. C., et al. (2008). L-theanine, a natural constituent in tea, and its effect on mental state. Asia Pacific Journal of Clinical Nutrition, 17(S1), 167-168. [https://apjcn.nhri.org.tw/server/APJCN/17%20Suppl%201//167.pdf]

White, D. J., et al. (2016). Anti-stress, behavioural and magnetoencephalography effects of an l-theanine-based nutrient drink: a randomised, double-blind, placebo-controlled, crossover trial. Nutrients, 8(1), 53. [https://www.mdpi.com/2072-6643/8/1/53]

Haskell, C. F., et al. (2008). The effects of L-theanine, caffeine and their combination on cognition and mood. Biological Psychology, 77(2), 113-122. [https://www.sciencedirect.com/science/article/abs/pii/S0301051107001573]

Owen, G. N., et al. (2008). The combined effects of L-theanine and caffeine on cognitive performance and mood. Nutritional Neuroscience, 11(4), 193-198. [https://www.tandfonline.com/doi/abs/10.1179/147683008X301513]

Lai, P. L., et al. (2013). Neurotrophic properties of the Lion’s mane medicinal mushroom, Hericium erinaceus (Higher Basidiomycetes) from Malaysia. International Journal of Medicinal Mushrooms, 15(6), 539-554. [https://www.ingentaconnect.com/content/ben/iim/2013/000000 15(06)/000539;jsessionid=1a8ojv0vnf1sw.x-ic-live-01]

Mori, K., et al. (2008). Nerve growth factor-inducing activity of Hericium erinaceus in 1321N1 human astrocytoma cells. Biological and Pharmaceutical Bulletin, 31(9), 1727-1732. [https://www.jstage.jst.go.jp/article/bpb/31/9/31_9_1727/_article]

Mori, K., et al. (2009). Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double-blind, placebo-controlled clinical trial. Phytotherapy Research, 23(3), 367-372. [https://onlinelibrary.wiley.com/doi/abs/10.1002/ptr.2634]

Fredholm, B. B., et al. (1999). Actions of caffeine in the brain with special reference to factors that contribute to its widespread use. Pharmacological Reviews, 51(1), 83-133. [https://jpet.aspetjournals.org/content/51/1/83.long]

Nehlig, A. (2010). Is caffeine a cognitive enhancer? Journal of Alzheimer’s Disease, 20(S1), 85-94. [https://content.iospress.com/articles/journal-of-alzheimers-disease/jad092200]

Mahadevan, S., & Park, Y. (2008). Multifaceted therapeutic benefits of Ginkgo biloba L.: chemistry, efficacy, safety, and uses. Journal of Food Science, 73(1), R14-R19. [https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1750-3841.2007.00597.x]

Yancheva, S., et al. (2009). Ginkgo biloba extract in dementia: a 22-week randomized, placebo-controlled, double-blind trial. Bulgarian Neurology, 10(4), 34-39. [https://www.researchgate.net/publication/280943884_Ginkgo_biloba_extract_in_dementia_a_22-week_randomized_placebo-controlled_double-blind_trial]

Mix, J. A., & Crews Jr, W. D. (2002). A double-blind, placebo-controlled, randomized trial of Ginkgo biloba extract EGb 761 in a sample of cognitively intact older adults: neuropsychological findings. Human Psychopharmacology: Clinical and Experimental, 17(6), 267-277. [https://onlinelibrary.wiley.com/doi/abs/10.1002/hup.412]

Ahlemeyer, B., & Krieglstein, J. (2003). Neuroprotective effects of Ginkgo biloba extract. Cellular and Molecular Life Sciences, 60(9), 1779-1792. [https://link.springer.com/article/10.1007%2Fs00018-003-3080-1]

Scholey, A. B., et al. (2010). Effects of American ginseng (Panax quinquefolius) on neurocognitive function: an acute, randomised, double-blind, placebo-controlled, crossover study. Psychopharmacology, 212(3), 345-356. [https://link.springer.com/article/10.1007%2Fs00213-010-196 4]

Reay, J. L., et al. (2006). Effects of Panax ginseng, consumed with and without glucose, on blood glucose levels and cognitive performance during sustained ‘mentally demanding’ tasks. Journal of Psychopharmacology, 20(6), 771-781. [https://journals.sagepub.com/doi/10.1177/0269881106061516]

Lee, S. H., et al. (2011). Panax ginseng enhances cognitive performance in Alzheimer disease. Alzheimer Disease & Associated Disorders, 25(3), 230-237. [https://journals.lww.com/alzheimerjournal/Abstract/2011/07000/Panax_ginseng_Enhances_Cognitive_Performance_in.4.aspx]

Darbinyan, V., et al. (2000). Rhodiola rosea in stress-induced fatigue: a double-blind, crossover study. Phytomedicine, 7(5), 365-371. [https://www.sciencedirect.com/science/article/abs/pii/S0944711300800555]

Spasov, A. A., et al. (2000). A double-blind, placebo-controlled pilot study of the stimulating and adaptogenic effect of Rhodiola rosea SHR-5 extract on the fatigue of students caused by stress during an examination period with a repeated low-dose regimen. Phytomedicine, 7(2), 85-89. [https://www.sciencedirect.com/science/article/abs/pii/S0944711300800373]

Mao, J. J., et al. (2015). Rhodiola rosea versus sertraline for major depressive disorder: A randomized placebo-controlled trial. Phytomedicine, 22(3), 394-399. [https://www.sciencedirect.com/science/article/abs/pii/S0944711315000348]

Amsterdam, J. D., et al. (2012). A randomized, double-blind, placebo-controlled trial of oral Matricaria recutita (chamomile) extract therapy for generalized anxiety disorder. Journal of Clinical Psychopharmacology, 32(4), 758-765. [https://journals.lww.com/psychopharmacology/Abstract/2012/08000/A_Randomized,_Double_Blind,_Placebo_Controlled.36.aspx]

Comments are closed.